1.1 本试验方法涵盖了在适当的有机溶剂中测定亚砜酰胺不溶性杂质的一般程序。 1.2 以国际单位制表示的数值应视为标准。括号中给出的值仅供参考。 1.3 本标准并非旨在解决与其使用相关的所有安全问题（如有）。本标准的用户有责任在使用前制定适当的安全、健康和环境实践，并确定监管限制的适用性。 1.4 本国际标准是根据世界贸易组织技术性贸易壁垒（TBT）委员会发布的《关于制定国际标准、指南和建议的原则的决定》中确立的国际公认标准化原则制定的。 ====意义和用途====== 4.1 磺酰胺的化学纯度和功能性能会降低，通常表现为含量下降、游离胺释放和不溶物增加。本试验方法可作为此类退化的指示。 4.2 由于MBT（巯基苯并噻唑二硫化物）是亚砜酰胺的主要降解产物，因此测定MBT是评估亚砜酰胺可能降解的一种方法。不溶物是指亚砜酰胺中的巯基苯并噻唑二硫化物（MBTS）含量；MBTS是磺酰胺的主要降解产物。巯基苯并噻唑（MBT）的胺盐也可能不溶。然而，在磺酰胺降解过程中也可能产生某些可溶性物质。因此，不溶物不是纯度的绝对测量值，实际上可以随着磺酰胺降解而减少。

1.1 This test method covers a general procedure for the determination of insoluble impurities of sulfenamides in suitable organic solvents. 1.2 The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.4 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee. ====== Significance And Use ====== 4.1 Sulfenamides can degrade in chemical purity and functional performance, usually characterized by a drop in assay, a release of free amine, and an increase in insolubles. This test method may be used as an indication of such degradation. 4.2 Since MBTS (mercaptobenzothiazole disulfide) is a primary degradation product of sulfenamides, the determination of MBTS is a means of assessing possible degradation of sulfenamides. Insolubles are a means of mercaptobenzothiazyl disulfide (MBTS) content of the sulfenamide; MBTS is a primary degradation product of sulfenamides. Amine salts of mercaptobenzothiazole (MBT) may also be insoluble. However, certain soluble species may also be generated during sulfenamide degradation. Consequently, insolubles are not an absolute measure of purity and can actually decrease with sulfenamide degradation.