1.1本规范涵盖了外科植入物应用中磷酸钙涂层的材料要求。 1.2在颗粒和整体形式中，磷酸钙材料系统在生物反应方面具有良好的特性 (1,2) 2. 和实验室特征 (2-4) . 几份出版物 (5-10) 记录了 体外 和 体内 选定磷酸钙涂层系统的性能。 1.3本规范包括羟基磷灰石涂层、磷酸三钙涂层或其组合，无论是否有意添加其他陶瓷或金属， 3. 并通过包括但不限于以下方法应用:( 1. )机械捕捉( 2. )等离子喷涂沉积( 3. )浸渍/烧结( 4. )电泳沉积( 5. )陶瓷化，以及( 6. )溅射。 1.4基底可包括光滑、多孔、纹理和其他可植入地形形式。 1.5本规范不包括可能含有钙和磷离子物种的有机涂层。 1.6 警告- 环保局和许多国家机构已将汞指定为一种有害物质，可导致中枢神经系统、肾脏和肝脏损害。汞或其蒸汽可能对健康有害，并对材料具有腐蚀性。处理汞和含汞产品时应小心。有关详细信息，请参阅适用的产品材料安全数据表（MSDS）和EPA网站(http://www.epa.gov/mercury/faq.htm)了解更多信息。用户应意识到，州法律可能禁止在您所在州销售汞或含汞产品，或同时销售两者。

1.1 This specification covers the material requirements for calcium phosphate coatings for surgical implant applications. 1.2 In particulate and monolithic form, the calcium phosphate materials system has been well-characterized regarding biological response (1,2) 2 and laboratory characterization (2-4) . Several publications (5-10) have documented the in vitro and in vivo properties of selected calcium phosphate coating systems. 1.3 This specification includes hydroxylapatite coatings, tricalcium phosphate coatings, or combinations thereof, with or without intentional minor additions of other ceramic or metallic, 3 and applied by methods including, but not limited to, the following: ( 1 ) mechanical capture, ( 2 ) plasma spray deposition, ( 3 ) dipping/sintering, ( 4 ) electrophoretic deposition, ( 5 ) porcelainizing, and ( 6 ) sputtering. 1.4 Substrates may include smooth, porous, textured, and other implantable topographical forms. 1.5 This specification excludes organic coatings that may contain calcium and phosphate ionic species. 1.6 Warning— Mercury has been designated by EPA and many state agencies as a hazardous material that can cause central nervous system, kidney, and liver damage. Mercury, or its vapor, may be hazardous to health and corrosive to materials. Caution should be taken when handling mercury and mercury-containing products. See the applicable product Material Safety Data Sheet (MSDS) for details and EPA’s website (http://www.epa.gov/mercury/faq.htm) for additional information. Users should be aware that selling mercury or mercury-containing products, or both, in your state may be prohibited by state law.