This paper describes the Methods and Data Comparability Board (MDCB), which was formed at the recommendation of the Intergovernmental Task Force on Monitoring Water Quality (ITFM). The work of the MDCB is based, in part, on the recommendations of the Data Collection Methods Task group that operated under ITFM auspices. It provides the framework and the forum for comparing, evaluating, and promoting monitoring approaches that can be implemented in all appropriate water quality monitoring programs. While its mission is to promote and coordinate the collection of comparable water quality data, the MDCB will, more specifically: prioritize methods and parameters in need of comparability assessments; develop technical guidelines for ensuring and documenting data comparability; develop and promote a performance based methods system; participate in establishing reference methods; develop technical guidelines for methods validation; promote a national laboratory accreditation program and prelaboratory certification program; and, identify and support programmatic needs for methods comparison exercises.