In high-rise buildings, modulating stair pressurization systems are frequently used in "Smokeproof Enclosure" designs. This is especially true for stairpressurization involving design doors open. One important design consideration is the time it takes to sense changes in air pressure and then respond withchanges in air supply. This paper investigates the potential impact that the opening and closing of stair doors could have on the operation of a modulatingstair pressurization system, and suggests potential design features to minimize these effects. Airflow modeling software was utilized to model an examplesystem and characterize its ability to maintain the required pressure range.