ISO 13408-2:2003规定了作为无菌加工保健产品的一部分的过滤消毒的要求。它还提供过滤用户的指导，以了解灭菌过滤过程的设置，验证和常规操作的一般要求，用于保健产品的无菌加工。 ISO 13408-2:2003不适用于去除病毒。灭菌过滤不适用于含有大于过滤器孔径（如细菌全细胞疫苗）的有效成分的颗粒的流体

ISO 13408-2:2003 specifies requirements for sterilizing filtration as part of aseptic processing of health care products. It also offers guidance to filter users concerning general requirements for set-up, validation and routine operation of a sterilizing filtration process, to be used for aseptic processing of health care products. ISO 13408-2:2003 is not applicable to removal of viruses. Sterilizing filtration is not applicable to fluids containing particles as effective ingredient larger than the pore size of a filter (e.g. bacterial whole-cell vaccines).