1.1 本试验方法包括用液相色谱法（LC）直接注射并用串联质谱法（MS/MS）检测水中涕灭威、涕灭碳砜、呋喃丹、灭多威、恶氨酰和噻虫酮（在本试验方法中统称为氨基甲酸酯）。这些分析物通过该测试方法进行定性和定量测定。该测试方法遵循多重反应监测（MRM）质谱法。 1.2 氨基甲酸酯的检测验证水平（DVL）和报告范围列于 表1 . 1.2.1 DVL的浓度要求至少比报告限值（RL）低3倍，且信噪比大于3:1。 图1 显示主要单反应监测（SRM）转换的信噪比，以及 图2 显示了氨基甲酸酯DVL处的确认SRM转变。 1.3 单位- 以国际单位制表示的数值应视为标准。本标准不包括其他计量单位。 1.4 本标准并非旨在解决与其使用相关的所有安全问题（如有）。 本标准的使用者有责任在使用前制定适当的安全、健康和环境实践，并确定监管限制的适用性。 1.5 本国际标准是根据世界贸易组织技术性贸易壁垒委员会发布的《关于制定国际标准、指南和建议的原则的决定》中确立的国际公认的标准化原则制定的。 ====意义和用途====== 5.1 这种测试方法是由美国开发的。 美国环保局第5区芝加哥地区实验室（CRL）。 5.2 这个 N -氨基甲酸甲酯（NMC）农药:涕灭威、呋喃丹、灭多威、恶氨酰和硫番毒素已被美国环保局认定为通过一种常见机制发挥作用。这些通过降低酶的能力来影响神经系统。在评估NMC的食品、饮用水和住宅风险时，酶抑制是EPA监管关注的主要毒理学效应。在该国大部分地区，饮用水源中的NMC残留量不太可能对多- 途径累积暴露。浅层私人水井穿过高渗透性土壤延伸到浅层酸性地下水中，这是美国环保局认为最脆弱的饮用水。涕灭威砜和涕灭威亚砜是涕灭威的分解产物，由于其毒性作用，也应进行监测。 4. 5.3 本试验方法已被研究用于所选氨基甲酸酯的试剂、表面和饮用水:涕灭威、涕灭碳砜、涕杀威亚砜、呋喃丹、灭多威、恶多威和硫法诺。

1.1 This test method covers the determination of aldicarb, aldicarb sulfone, aldicarb sulfoxide, carbofuran, methomyl, oxamyl, and thiofanox (referred to collectively as carbamates in this test method) in water by direct injection using liquid chromatography (LC) and detected with tandem mass spectrometry (MS/MS). These analytes are qualitatively and quantitatively determined by this test method. This test method adheres to multiple reaction monitoring (MRM) mass spectrometry. 1.2 The Detection Verification Level (DVL) and Reporting Range for the carbamates are listed in Table 1 . 1.2.1 The DVL is required to be at a concentration at least 3 times below the Reporting Limit (RL) and have a signal/noise ratio greater than 3:1. Fig. 1 displays the signal/noise ratios of the primary single reaction monitoring (SRM) transitions, and Fig. 2 displays the confirmatory SRM transitions at the DVLs for the carbamates. 1.3 Units— The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.5 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee. ====== Significance And Use ====== 5.1 This test method has been developed by U.S. EPA Region 5 Chicago Regional Laboratory (CRL). 5.2 The N -methyl carbamate (NMC) pesticides: aldicarb, carbofuran, methomyl, oxamyl, and thiofanox have been identified by EPA as working through a common mechanism. These affect the nervous system by reducing the ability of enzymes. Enzyme inhibition was the primary toxicological effect of regulatory concern to EPA in assessing the NMC’s food, drinking water, and residential risks. In most of the country, NMC residues in drinking water sources are at levels that are not likely to contribute substantially to the multi-pathway cumulative exposure. Shallow private wells extending through highly permeable soils into shallow, acidic ground water represent what the EPA believes to be the most vulnerable drinking water. Aldicarb sulfone and aldicarb sulfoxide are breakdown products of aldicarb and should also be monitored due to their toxicological effects. 4 5.3 This test method has been investigated for use with reagent, surface, and drinking water for the selected carbamates: aldicarb, aldicarb sulfone, aldicarb sulfoxide, carbofuran, methomyl, oxamyl, and thiofanox.