目前许多分析NDMA的实验室使用各种不同的分析方法和技术。样本量、保存、提取方法和仪器都是该目标分析中的变量。虽然在低ppt范围内分析N-亚硝基二甲胺（NDMA）的实验室数量继续增加，但由于所采用的样品制备和分析方法的可变性，它们产生的数据无法轻易相互参照。本研究的重点是开展一项性能评估研究，以确定这些技术和方法在试剂水和经处理的循环水中对NDMA进行低水平分析的可靠性。 NDMA分析的相关成本、控制条件以及开展此类性能研究的协调是非常重要的。因此，卫生服务部在开展这项盲目绩效评估（PE）研究时制定了明确的目标。本研究的目标是:控制聚乙烯样品的生成、储存和运输，以确保参与本研究的所有实验室分析相同的样品，并制定质量控制以监控该过程；加标NDMA浓度水平，包括试剂水和处理循环水基质的当前和拟议行动水平的监测要求，并确认2。 0 ppt和20.0 ppt浓度水平；确定参与实验室在试剂水和经处理的循环水基质中生成的NDMA数据的可靠性；并确定特定技术、参数或仪器在NDMA数据集中产生的影响程度（如有）。这项研究的工作分为位于洛杉矶的加利福尼亚州卫生服务部实验室-卫生和辐射实验室分部（SRLB South）和位于加利福尼亚州喷泉谷的奥兰治县水区实验室（OCWD）。OCWD生成经处理的循环水基质和加标样品，而SRLB- South生成试剂水基质和加标样品。包括7个参考文献和表格。

Many of the current laboratories that analyze for NDMA, use a variety of different analytical approaches and techniques. Sample volume, preservation, extraction method, and instrumentation are all variables within the analysis of this target. While the number of laboratories analyzing for N-Nitrosodimethylamine (NDMA) at the low ppt range continues to increase, the data generated by them cannot be easily referenced against one another, because of the variability in sample preparation and analytical methods employed. The focus of this research was to develop a performance evaluation study to determine the reliability of these techniques and methods for the low level analysis of NDMA, in both reagent water and treated recycled water. The costs associated for the analysis of NDMA, the control conditions, and coordination for developing such a performance study is significant. Thus, the Department of Health Services developed clear objectives while developing this blind performance evaluation (PE) study. The objectives of this study were to: control the generation, storage, and shipment of the PE samples to ensure that all laboratories participating within this study analyzed the same samples, and develop quality controls to monitor this process; spike NDMA concentration levels that cover the monitoring requirements of both the current and proposed action levels, for reagent water and treated recycled water matrices, and confirm both the 2.0 ppt and 20.0 ppt concentration levels; determine the reliability of NDMA data generated by the participating laboratories in both reagent water and treated recycled water matrices; and, determine the extent of influence (if any) that specific techniques, parameters or instrumentation produce within the NDMA data set. The study's efforts were divided between California's Department of Health Services Laboratory - Sanitation and Radiation Laboratories Branch (SRLB-South) in Los Angeles and the Orange County Water District's Laboratory (OCWD) in Fountain Valley, California. OCWD generated the treated recycled water matrix and spiked samples, while SRLB-South generated the reagent water matrix and spiked samples. Includes 7 references, tables.