本文以一个研发综合体为例，研究并说明如何使用混合方法为大型研发综合体提供最佳暖通空调解决方案，以满足能源和舒适性要求。研发中心由25层组成，包括4层地下，总可用空间为30万平方米。根据荷载特性，综合体分为两个区域:外部区域和内部区域。外部区域暴露在室外天气条件下，因此它们的热负荷和冷负荷在一天中波动更大。为了应对这些不断变化的负荷，总共使用了273个可变制冷剂流量（VRF）系统和3142台不同类型的室内机。这些系统配备高效变频驱动涡旋压缩机。内部区域有相对稳定的热负荷和冷负荷，因此由4台吸收式制冷机和3台离心式制冷机提供服务。 本文将从建筑概述和暖通空调系统设计目标开始，然后从能源效率、人体舒适性、初始投资和系统生命周期成本等方面对不同的暖通空调系统设计方案进行深入分析和比较。为了研究不同类型的室内机对室内温度和气流分布的影响，进行了广泛的CFD研究。最后，我们将提出一种优化运行算法，并用现场测试数据证明其节能潜力。引用:2016年年度会议，密苏里州圣路易斯，会议论文

This paper uses a R&D complex as a case study to examine and illustrate how a hybrid approach can be used to provide an optimal HVAC solution for massive R&D complexes to meet energy and comfort requirements. The R&D complex consists of 25 floors including 4 subterranean floors with a total usable space of 300,000 m2. According to the load characteristics, the complex is divided into two areas: exterior zones and interior zones. The exterior zones are exposed to the outdoor weather conditions, thus their heating and cooling loads fluctuate more throughout the day. To deal with these changing loads, a total of 273 variable refrigerant flow (VRF) systems with 3142 indoor units of various types are used. These systems are equipped with high efficiency inverter driven scroll compressors. The interior zones have a relatively stable heating and cooling loads, are hence served by 4 absorption chillers and 3 three centrifugal chillers. This paper will begin with an architecture overview and objectives of HVAC systems design, followed by in-depth analysis and comparisons of different HVAC system design options in terms of energy efficiency, human comfort, initial investment and system life cycle costs. Extensive CFD studies were conducted to investigate the impact of different types of indoor units on indoor temperature and air flow distribution. Finally, we will present an optimal operation algorithm and demonstrate its energy saving potential with field test data.