The bacterial nutrient of greatest concern in biological filtration and distribution system regrowth is biodegradable organic matter (BOM). BOM can be removed in any microbiological process which takes place between the raw water source and the consumer's tap. Essentially, all of this removal takes place in biofilms. The existence of these microbiological processes implies that both the treatment plant and the distribution system should be thought of as bioreactors. In general, it is preferable to maximize the performance of the treatment plant so that the efficiency of the distribution system as a bioreactor is minimized. This reduces undesirable bacterial growth and minimizes levels of disinfection byproducts and, potentially, corrosion. This paper discusses the removal of BOM in both water treatment and distribution within the context of a unifying concept, the bioreactor time or biotime. From this perspective, the objective should be to maximize the biotime of the treatment plant and minimize the biotime of the distribution system.