本文件以及ISO 16000-38规定了使用累积采样和高效液相色谱（HPLC）结合串联质谱（MS-MS）或高分辨率质谱（HRMS）测定室内空气中一级、二级和三级脂肪胺和芳香胺质量浓度的测量方法。本文件涵盖了分析程序。ISO 16000-38涵盖了取样程序和取样器的制造。 本文件描述了胺的色谱和质谱技术规范。测量结果以µg/m3表示。 虽然主要用于测量表A.1和A.2中列出的胺，但也可用于测量室内空气中的其他胺。本文件给出了包含其他胺的说明和程序。 本文件关于室内空气中胺浓度的适用范围取决于校准线的线性范围，因此取决于气体样品体积（此处:从5升到100升）、洗脱液体积（从1毫升到5毫升）、进样体积（从1微升到10微升）和分析设备的灵敏度（例如，从2微克到2纳克胺的线性范围）。对于普通分析设备（如Waters“TQD”）而言，应用范围预计从大约0002µg/m3（100 l样品）到2000µg/m3（5 l样品）对于表A.1和A.2中列出的大多数胺。乙醇胺衍生物的分析灵敏度通常是普通胺的10倍左右，短链脂肪胺的分析灵敏度通常是普通胺的10倍左右。 分析方法的性能数据见附录B，尤其是表B。 1和B.2。 如果检测限足够，本文件也可用于测定水中的胺。 本文件不包括室内空气（或水样）中的异氰酸酯作为相应胺的测定（ISO 17734-1和ISO 17734-2涵盖）。交叉引用:ISO 16000-38ISO 9702:1996ISO 17734ISO 12219-1ISO/IEC 17025:2017ISO 12219-4ISO 16000-28VDI 2467-2:1991购买本文件时可用的所有现行修订版均包含在购买本文件中。

This document, along with ISO 16000-38, specifies the measurement method for determining the mass concentration of primary, secondary and tertiary aliphatic and aromatic amines in indoor air using accumulated sampling and high-performance liquid chromatography (HPLC) coupled with tandem mass spectrometry (MS-MS) or high-resolution mass spectrometry (HRMS). The analytical procedure is covered by this document. The sampling procedure and the manufacturing of the samplers are covered by ISO 16000-38. This document describes specifications for the chromatography and the mass spectroscopy for the amines. Measurement results are expressed in µg/m3. Although primarily intended for the measurement of amines listed in Tables A.1 and A.2, it can also be used for the measurement of other amines in indoor air. This document gives instructions and describes procedures for the inclusion of other amines. The range of application of this document concerning the concentrations of amines in indoor air depends on the linear range of the calibration line and hence on the gas sample volume (here: from 5 l up to 100 l), the eluate volume (from 1 ml up to 5 ml), the injection volume (from 1 µl up to 10 µl) and the sensitivity of the analytical equipment (e.g. linear range from 2 pg up to 2 ng amine). The range of application can be expected to be from approximately 0,002 µg/m3(100 l sample) up to 2 000 µg/m3(5 l sample) for a common analytical equipment (e.g. Waters „TQD“) for the majority of the amines listed in Tables A.1 and A.2. The analysis of derivatives of ethanolamine is usually about 10 times more sensitive and the analysis of short-chained aliphatic amines is usually about 10 times less sensitive than the analysis of an average amine. The performance data of the analytical method is given in Annex B, particularly in Tables B.1 and B.2. This document can be used also for the determination of amines in water if the detection limit is sufficient. This document does not cover the determination of isocyanates in indoor air (nor in water samples) as corresponding amines (covered by ISO 17734-1 and ISO 17734-2).Cross References:ISO 16000-38ISO 9702:1996ISO 17734ISO 12219-1ISO/IEC 17025:2017ISO 12219-4ISO 16000-28VDI 2467-2:1991All current amendments available at time of purchase are included with the purchase of this document.