1.1 本程序包括使用液相色谱法（LC）和串联质谱法（MS/MS）检测水基质中选定的全氟和多氟烷基物质（PFASs）。这些分析物通过本试验方法进行定性和定量测定。该试验方法遵循一种称为选择性反应监测（SRM）或有时称为多反应监测（MRM）的技术。这不是饮用水方法；尚未在饮用水基质上评估该试验方法的性能。 1.2 方法检测限（MDL） 2. 和报告范围 3. 对于目标分析物，见 表1 . 本试验方法报告限值的目标浓度为10 开发时大多数目标分析物的纳克/升。 1.2.1 本试验方法中的报告极限是记录为未检测数据的最小值。如果您的实验室在较低浓度下满足本试验方法的最低性能要求，并且本试验方法基于性能，并且允许修改以提高性能，则可以降低报告限制。方法检测限和报告限之间的分析物检测是估计浓度，在本试验方法之后不报告。在大多数情况下，报告限值为1级校准标准的浓度，如表4所示，考虑到50 % 用甲醇稀释。 它高于FHEA和FOEA的1级校准浓度，这些化合物可以在1级浓度下鉴定，但在这个较低的峰值水平下，重复之间的标准偏差导致了更高的报告限。 1.3 以国际单位制表示的数值应视为标准值。本标准不包括其他计量单位。 1.4 本标准并非旨在解决与其使用相关的所有安全问题（如有）。本标准的用户有责任在使用前制定适当的安全、健康和环境实践，并确定监管限制的适用性。 1.5 本国际标准是根据世界贸易组织技术性贸易壁垒（TBT）委员会发布的《关于制定国际标准、指南和建议的原则的决定》中确立的国际公认标准化原则制定的。 ====意义和用途====== 5.1 PFASs广泛应用于各种工业和商业产品中；它们具有持久性、生物累积性，在环境中无处不在。据报道，PFASs具有发育毒性、肝毒性、免疫毒性和激素紊乱。来自美国的全氟烷基毒理学概况草案。 S、 卫生和公共服务部可用。 6. 在土壤、淤泥、表面和饮用水中检测到PFASs。因此，需要一种快速、简单、可靠的方法来测定水基质中痕量水平的这些化合物，以了解暴露的来源和途径。 5.2 本试验方法已用于选定PFASs的试剂、表面、污泥和废水。本试验方法尚未在饮用水基质上进行评估。

1.1 This procedure covers the determination of selected per- and polyfluoroalkyl substances (PFASs) in a water matrix using liquid chromatography (LC) and detection with tandem mass spectrometry (MS/MS). These analytes are qualitatively and quantitatively determined by this test method. This test method adheres to a technique known as selected reaction monitoring (SRM) or sometimes referred to as multiple reaction monitoring (MRM). This is not a drinking water method; performance of this test method has not been evaluated on drinking water matrices. 1.2 The method detection limit (MDL) 2 and reporting range 3 for the target analytes are listed in Table 1 . The target concentration for the reporting limit for this test method was 10 ng/L for most of the target analytes at the time of development. 1.2.1 The reporting limit in this test method is the minimum value below which data are documented as non-detects. The reporting limit may be lowered providing your lab meets the minimum performance requirements of this test method at the lower concentrations, this test method is performance based and modifications are allowed to improve performance. Analyte detections between the method detection limit and the reporting limit are estimated concentrations and are not reported following this test method. In most cases, the reporting limit is the concentration of the Level 1 calibration standard as shown in Table 4 for the PFASs after taking into account the 50 % dilution with methanol. It is above the Level 1 calibration concentration for FHEA and FOEA, these compounds can be identified at the Level 1 concentration but the standard deviation among replicates at this lower spike level resulted in a higher reporting limit. 1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.5 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee. ====== Significance And Use ====== 5.1 PFASs are widely used in various industrial and commercial products; they are persistent, bio-accumulative, and ubiquitous in the environment. PFASs have been reported to exhibit developmental toxicity, hepatotoxicity, immunotoxicity, and hormone disturbance. A draft Toxicological Profile for Perfluoroalkyls from the U.S. Department of Health and Human Services is available. 6 PFASs have been detected in soils, sludges, surface, and drinking waters. Hence, there is a need for quick, easy, and robust method to determine these compounds at trace levels in water matrices for understanding of the sources and pathways of exposure. 5.2 This test method has been investigated for use with reagent, surface, sludge and wastewaters for selected PFASs. This test method has not been evaluated on drinking water matrices.