ISO/TR 18161:2013描述了使用ISO 16100和ISO 18435规定应用程序之间信息交换要求的方法。该方法基于ISO 18435应用集成矩阵元素（AIME）/应用领域矩阵元素（ADME）模板与ISO 16100制造软件单元（MSU）能力概要的结合使用。 ISO/TR 18161:2013还提供了一个示例方法，用于描述集成智能泵应用程序的互操作性要求，该应用程序包括泵控制应用程序和泵诊断应用程序。

ISO/TR 18161:2013 describes an approach for using ISO 16100 and ISO 18435 to specify information exchange requirements between applications. This approach is based on the use of ISO 18435 application integration matrix element (AIME)/application domain matrix element (ADME) templates in conjunction with ISO 16100 manufacturing software unit (MSU) capability profiles. ISO/TR 18161:2013 also provides an example approach as applied to describing the interoperability requirements of the integrated smart pump application, which comprises the pump control application and the pump diagnostics application.