本文件规定了用液相色谱结合串联质谱法（LC-MS/MS）测定三聚氰胺和三聚氰酸的方法。该方法已在一项实验室间研究中得到验证，该研究通过对牛奶基婴儿配方奶粉、大豆基婴儿配方奶粉、奶粉、全脂牛奶、大豆饮料和牛奶巧克力的添加样品进行分析，三聚氰胺的添加量为0.71？mg/kg至1.43？mg/kg，三聚氰酸的添加量为0.57？mg/kg至1.45？mg/kg。食品中三聚氰胺和三聚氰酸的定量限（LOQ）分别为0.05？mg/kg和0.25？mg/kg。 三聚氰胺和三聚氰酸的工作范围上限分别为10？mg/kg和25？mg/kg。

This document specifies a method for the determination of melamine and cyanuric acid with liquid chromatography in combination with tandem mass spectrometry (LC-MS/MS). The method has been validated in an interlaboratory study via the analysis of spiked samples of milk-based infant formula, soy-based infant formula, milk powder, whole milk, soy drink and milk chocolate ranging from 0,71？mg/kg to 1,43？mg/kg for melamine and 0,57？mg/kg to 1,45？mg/kg for cyanuric acid. The limits of quantification (LOQ) for melamine and cyanuric acid in food are 0,05？mg/kg and 0,25？mg/kg, respectively. The upper limit of the working range is up to 10？mg/kg for melamine and up to 25？mg/kg for cyanuric acid.