本技术规范（prCEN/TS 15606:2009）规定了高效液相色谱（HPLC）方法，用于测定食品中的乙酰磺胺酸K，阿斯巴甜，新西兰 - 二氢查耳酮和糖精。根据IUPAC协调协议[2]，以下分析物基质组合，通过协同试验对透析程序进行了充分验证[1]: 乙酰磺胺酸K和阿斯巴甜在水性饮料，水果饮料，芝士蛋糕与饼干基地，罐装汤和速溶巧克力饮料; 水果饮料中的糖精，水果饮料，饼干基地和罐装汤的芝士蛋糕; 水性饮料中的新橙皮苷 - 二氢查耳酮，水果饮料和罐装汤

This Technical Specification (prCEN/TS 15606:2009) specifies a high performance liquid chromatographic (HPLC) method for the determination of acesulfame-K, aspartame, neohesperidine-dihydrochalcone and saccharin in foodstuffs. The method has been fully validated [1] for the dialysis procedure through collaborative trial, according to the IUPAC Harmonised Protocol [2], on the following analyte matrix combinations: acesulfame-K and aspartame in water-based drink, fruit-based drink, cheesecake with biscuit base, canned soup and instant chocolate drink; saccharin in water-based drink, fruit-based drink, cheesecake with biscuit base and canned soup; neohesperidine-dihydrochalcone in water-based drink, fruit-based drink and canned soup.