开展了一个为期五年的多学科研究项目，以评估使用处理后的废水补充地下水对健康的影响。这项研究的重点是加利福尼亚州洛杉矶县的惠蒂尔·莱恩斯地下水补给项目，自1962年以来，该项目一直采用进口河水、雨水和回收废水的混合物进行补给。确定了以下五项研究任务:根据微生物和无机化学含量对地下水、再生水和其他补给源的质量进行表征；对地下水、再生水和其他补给源进行毒理学和化学研究，以分离和鉴定对健康有重要意义的有机成分； 渗滤研究，以评估土壤对再生水中无机和有机化学物质的衰减效果；水文地质研究，以确定再生水通过地下水的运动以及再生水对市政供水的相对贡献；对饮用再生水的人群进行流行病学研究，以确定他们的健康特征是否与人口统计学上相似的对照人群存在显著差异。研究结果表明，目前用于补给的再生水比例对地下水质量或人类健康没有可测量的影响。包括使用再生水优化地下水补给的建议。 包括48个参考文献、表格和图表。

A five-year multi-disciplinary research project was undertaken to evaluate the effects on health of using treated wastewater for groundwater replenishment. The study focused on the Whittier Narrows Groundwater Replenishment Project in Los Angeles County, California, where replenishment with a mixture of imported river water, stormwater, and reclaimed wastewater has been practiced since 1962. The following five research tasks were identified: characterization of the quality of the groundwater, reclaimed water, and other replenishment sources in terms of their microbiological and inorganic chemical content; toxicological and chemical studies of groundwater, reclaimed water, and other replenishment sources to isolate and identify organic constituents of significance to health; percolation studies to evaluate the efficacy of soil for attenuating inorganic and organic chemicals in reclaimed water; hydrogeological studies to determine the movement of reclaimed water through groundwater and the relative contribution of reclaimed water to municipal water supplies; and epidemiological studies of populations ingesting reclaimed water to determine whether their health characteristics differed significantly from a demographically similar control population. Results of the study showed that the proportion of reclaimed water currently used for replenishment had no measurable impact on either groundwater quality or human health. Recommendations for optimization of groundwater replenishment with reclaimed water are included. Includes 48 references, tables, figure.