本powerpoint演示文稿首先简要概述了腺病毒的紫外线（UV）灭活。这项研究的动机包括以下几点: 证明腺病毒不是真的 极耐紫外线； 紫外线可以提供类似程度的病毒 氯灭活； 地下水法则表明紫外线不能被吸收 在紫外线下验证4-log病毒灭活 核反应堆和 这项研究的目的是证明它的可行性，并增强 之前的实验室工作。实验设计包括: 验证MP有效性的台架实验 UV与LP； 制定紫外线反应器测试计划，涵盖 UVT和流量的范围； 与外部专家（美国环境保护局和 （州监管机构）获取该计划的反馈；和 进行CB和现场规模的反应堆试验，并 评估数据。腺病毒检测面临的挑战包括: 能够在反应器中达到的滴度（1-5 x 105）， 难以获得高滴度腺病毒库； 与致病性病毒合作 所需的特殊处理和预防措施；在反应堆中实现高对数减少 受进水滴度和化验控制； 符合验证系数的剂量，紫外线反应器条件的1.28验证系数，以及 4-log所需的目标高出28%；和 约235mJ/cm²。包括表格、数字。

This powerpoint presentation begins by providing a brief overview of ultraviolet (UV) inactivation of Adeno. The motivation for the study included the following points: demonstrate that adenovirus is not really extremely resistant to UV; UV can provide a similar level of virus inactivation as chlorine; Ground Water Rule suggests that UV cannot be validated for 4-log virus inactivation in a UV reactor; and, the study set out to prove it could and to augment the previous lab work. The experimental desgin included: Bench Experiments to verify efficacy of MP UV vs LP; establish a UV Reactor test plan to cover a range of UVT and flows; interact with outside experts (US Environmental Protection Agency and State Regulators) to get feedback on the plan; and, carry out CB and field-scale reactor tests and evaluate data. Challenges for Adeno Testing include the following: Titer able to achieve in Reactor (1-5 x 105), hard to obtain high titer adenovirus stocks; working with a pathogenic virus required special handling and precautions; achieving high log reduction in reactor governed by influent titer and assay; meeting a dose with validation factors, 1.28 validation factor for UV reactor conditions and 28% higher target needed for 4-log; and, ~235 mJ/cm². Includes tables, figures.