本标准提供了通过琼脂稀释和肉汤微量稀释测定厌氧菌最低抑制浓度的参考方法。临床和实验室标准协会标准M11——厌氧菌的抗生素敏感性试验方法描述了参考标准琼脂稀释法（Wadsworth）和替代肉汤微量稀释法。在过去几年中，许多厌氧细菌的耐药性模式发生了显著变化，导致许多物种缺乏可预测性。建议出于监测目的和特定临床情况对厌氧菌进行敏感性测试。琼脂稀释法非常适合于监测试验和研究。它也是与其他方法进行比较的标准。 另一种方法，肉汤微量稀释法，非常适合医学实验室，但目前仅限于检测类杆菌SSPP。和Parabacteroidesspp。微生物和选定的抗菌剂。每个程序的质量控制标准如下: 也有描述。该标准化程序与M100表格结合使用时，包括药物选择、解释、质量控制和抗生谱报告的最新信息。当发现新问题或对这些标准进行改进时，将在本标准和M100的未来版本中进行修改。

This standard provides reference methods for determining minimal inhibitory concentrations of anaerobic bacteria by agar dilution and broth microdilution.Clinical and Laboratory Standards Institute standard M11 -Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteriadescribes the reference standard agar dilution method (Wadsworth) and the alternative broth microdilution method.Antimicrobial resistance patterns for many anaerobic bacteria have changed significantly over the past several years, resulting in a lack of predictability for many species. Susceptibility testing of anaerobes is recommended for surveillance purposes and for specific clinical situations. The agar dilution method is well suited for surveillance testing and research. It is also the standard with which other methods are compared.The alternative method, broth microdilution, is well suited for the medical laboratory but is currently limited to testingBacteroidesspp. andParabacteroidesspp. organisms and selected antimicrobial agents. QC criteria for each procedure are also described.This standardized procedure, when used in conjunction with the M100 tables, includes the most current information for drug selection, interpretation, QC, and antibiogram reports. When new problems are recognized or improvements in these criteria are made, changes will be incorporated into future editions of this standard and in M100.