The Regional Municipality of Waterloo is located approximately 50 miles west of Toronto, Ontario, Canada. The region is responsible for water supply to three large urban centers: Waterloo, Kitchener, and Cambridge. Until 1992 when a surface water supply system was brought on line from the Grand River, the total population of the region was supplied by 126 wells. In the spring of 1993, the urban centers of the municipality experienced an outbreak of cryptosporidiosis with over 200 confirmed cases. This paper describes the events which took place before the outbreak and the actions which followed. The paper describes the following: the regional water supply system, the onset of the outbreak, response to the problem, findings and short term recommendations, plant performance review, plant startup and resumption of supply, long term optimization, and 1994 operational guidelines. The authors found that the water treatment plant was operating well at the time of the outbreak and met all regulatory water quality criteria. They conclude that almost any plant would be vulnerable to an outbreak of cryptosporidiosis under the current regulations.