本文件的目的是概述使用丝裂原刺激的外周血淋巴细胞进行双中心试验的最低要求，并采用质量控制措施，以初步评估参与大规模伤亡情况的个体。双中心检测是利用染色体损伤快速估计个体所接受的近似辐射剂量，以补充早期的伤亡临床分类。 本文件侧重于在初始评估模式中应用双中心分析的组织和操作方面。在ISO19238 本文件适用于单独工作的有经验的生物剂量测定实验室或合作实验室网络（如第7条所定义）。

The purpose of this document is to give an overview of the minimum requirements for performing the dicentric assay with quality control measures using mitogen stimulated peripheral blood lymphocytes for initial assessment of individuals involved in a mass casualty scenario. The dicentric assay is the use of chromosome damage to quickly estimate approximate radiation doses received by individuals in order to supplement the early clinical categorization of casualties. This document focuses on the organizational and operational aspects of applying the dicentric assay in an initial assessment mode. The technical aspects of the dicentric assay can be found in ISO？19238. This document is applicable either to an experienced biological dosimetry laboratory working alone or to a network of collaborating laboratories (as defined in Clause？7).