ISO 18218-1:2015是一种测定乙氧基化烷基酚（壬基酚乙氧基[NPEOn]和1≤ N≤ 16] 和辛基酚乙氧基化物[Opon with 1≤ N≤ 16] ）皮革的。这种直接法特别适用于检查大量皮革样品是否存在乙氧基化烷基酚的情况。 该方法需要使用高效液相色谱法（HPLC）和三重四极质谱仪（MSMS）来识别和定量乙氧基化烷基酚。 注1:在皮革行业，最常用的商用乙氧基化烷基酚是NPEO，平均为9 EO。对于40°C至55°C的典型皮革加工温度，它在水中有一个最佳浊点。 注2 ISO 18218- 1和ISO 18218-2使用不同的溶剂从皮革中提取乙氧基化烷基酚。因此，对于皮革中乙氧基化烷基酚的含量，这两种分析方法的趋势相似，但绝对结果不一定相同。

This document is a method for determining ethoxylated alkylphenols (APEO) [nonyphenol ethoxylate (NPEOn, where 2 ≤ n ≤ 16) and octylphenol ethoxylate (OPEOn, where 2 ≤ n ≤ 16)] in leather. This direct method is especially suitable when a larger number of leather samples are to be checked for the presence of ethoxylated alkylphenols. This method requires the use of liquid chromatography (LC) with a triple quadrupole mass spectrometer (MS/MS) to identify and quantify the ethoxylated alkylphenols. NOTE 1        In the leather industry, the most commonly used ethoxylated alkylphenol is the NPEO, with an average of 9 EO. It has an optimum cloud point in water for the typical leather processing temperatures of 40 °C to 55 °C. NOTE 2        This document and ISO 18218-2 use different solvents for the extraction of the ethoxylated alkylphenols from leather. Consequently, the two analytical methods are expected to give similar trends but not necessarily the same absolute result for the ethoxylated alkylphenol content in leather.