控制饮用水中的持久性病原体，如蓝氏贾第鞭毛虫囊肿、微小隐孢子虫囊肿和肠道病毒，越来越受到监管机构的重视。常用的化学和物理消毒方法在灭活这些病原体方面并不总是有效的。研究表明，反渗透膜的完整性并不能长期有效地抵抗病原体。如果膜元件在安装或运行过程中出现缺陷或故障，则必须采用完整性测试方法来检测微生物的潜在突破。本研究探讨了一种新的反渗透膜元件完整性评估方法，包括用聚苯乙烯荧光染料微球作为水性微生物的非生物替代指标进行挑战性测试。 MS2噬菌体是一种生物降解指示剂，与大小相似的微球同时使用。本研究的主要重点是建立这两种替代指标通过反渗透膜的通道之间的相关性。包括参考资料、表格、图表。

The control of persistent pathogens, such as Giardia lamblia cysts, Cryptosporidium parvumoocysts, and enteric viruses, in drinking water has been receiving increased attention fromregulatory authorities. Common methods of disinfection, both chemical and physical, are notalways effective in inactivating these pathogens. Studies have shown that reverse osmosis(RO) membranes may provide an effective barrier against pathogens, as long as the integrity ofthe membranes is not compromised. If a membrane element is defective or fails either duringinstallation or operation, integrity testing methods must be in place to detect potentialbreakthrough of microorganisms. This study investigated a new method of integrity assessmentfor RO membrane elements, consisting of challenge testing with polystyrene fluorescent-dyedmicrospheres as non-biological surrogate indicators of waterborne microorganisms. A biologicalsurrogate indicator, MS2 phage, was used simultaneously with microspheres of similar size.The main focus of this study was to establish a correlation between the passages of these twosurrogate indicators through the RO membranes. Includes reference, tables, figures.