本文件提供了一个确定参数设置和操作方法的原则，用于通过dGEMRIC和T2成像MRI评估人类关节软骨的组成和结构，并给出了一个典型的方法示例；每一种都是不同的MRI技术，可以无创观察软组织特征。 本文件中提供的方法旨在用于评估组织工程软骨或膝关节中使用的其他软骨再生产品的临床效果，也适用于评估其他关节中的再生软骨，尽管需要对参数进行一些修改。 本文描述了在1.5 T或3.0 T磁共振成像设备中使用dGEMRIC和T2标测技术时，对再生软骨中的含水量、糖胺聚糖（GAG）浓度以及胶原纤维的浓度和取向进行的纵向评估。

This document provides a principle to determine the parameter settings and operating methods for the evaluation of the composition and structure of articular cartilage by dGEMRIC and T2-mapping MRI in humans with a typical example of the methods; each are distinct MRI technologies that allow for noninvasive observation of soft tissue characteristics. The methods provided in this document are intended for application in the evaluation of the clinical effects of tissue-engineered cartilage or other cartilage regeneration products used in the knee joint, and are also applicable for the evaluation of regenerative cartilage in other joints, although some modification of parameters is needed. This document describes a longitudinal evaluation of the water content, the glycosaminoglycan (GAG) concentration, and the concentration and orientation of collagen fibres in regenerative cartilage when using dGEMRIC and T2-mapping techniques in 1,5 T or 3,0 T magnetic resonance imaging equipment.