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Guidance for dosimetry for sterile insects release programs 无菌昆虫释放计划剂量测定指南
发布日期: 2022-08-12
1.1本文件概述了用于害虫管理计划的活昆虫辐射诱导生殖灭菌所需遵循的剂量测定程序。这些昆虫的主要用途是无菌昆虫技术,在该技术中,大量繁殖性无菌昆虫被释放到田间,与同一物种的害虫种群交配,从而控制害虫种群。不育昆虫的第二个用途是作为饲养昆虫寄生蜂的良性宿主。第三种用途是测试果蝇和蛾子的检测陷阱,以及测试蛾子的交配破坏产品。本文件中概述的程序将有助于确保用γ、电子或X射线电离辐射处理的昆虫- 射线源接收预定范围内的吸收剂量。有关昆虫杀菌具体应用的有效剂量范围或确定有效剂量范围的方法的信息不在本文件的范围内。 注1——剂量测定只是总质量保证计划的一个组成部分,以确保辐照昆虫经过充分消毒,具有充分竞争力,或以其他方式适合其预期用途。 1.2本文件提供了这些类型辐照器的昆虫辐照剂量测定信息:自给式干式储存137Cs或60Co辐照器,自给式低剂量- 能量X射线辐射器(最大处理能量从150 keV到300 keV)、大型伽马辐射器和电子加速器(电子和X射线模式)。 注2——关于安装鉴定、操作鉴定、性能鉴定和常规产品处理中应遵循的剂量测定程序的更多详细信息,请参见ISO/ASTM规范51608(能量超过300keV的X射线[韧致辐射]设备处理)、51649(电子束设备)、51702(大型伽马设备),和52116(自给式干储存伽马设施),以及参考文献(1)2(自给X- 射线设备)。 1.3以国际单位表示的数值应视为标准值。除分钟(min)小时(h)和天(d)的非SI单位外,本标准中不包括其他计量单位。这些非国际单位可在国际单位制内使用。 1.4本文件是为正确实施和利用辐射处理提供建议的一套标准之一。本标准旨在与ISO/ASTM规程52628结合阅读。 1.5昆虫灭菌的吸收剂量通常在20 Gy至600 Gy范围内。 1.6本文件通篇特别提及昆虫的生殖绝育。 它同样适用于其他类群无脊椎动物的辐射灭菌(例如,蜱螨纲、腹足纲),以及用于其他目的的活昆虫或其他无脊椎动物辐射(例如,诱导突变),前提是吸收剂量在1.5规定的范围内。 1.7本文件还涵盖了辐射敏感指示器的使用,用于直观和定性指示昆虫已受到辐射(见ISO/ASTM指南51539)。 1.8本标准并不旨在解决与其使用相关的所有安全问题(如有)。本标准的使用者有责任在使用前制定适当的安全、健康和环境实践,并确定监管限制的适用性。 1.9本国际标准是根据世界贸易组织技术性贸易壁垒(TBT)委员会发布的《关于制定国际标准、指南和建议的原则的决定》中确立的国际公认标准化原则制定的。
1.1 This document outlines dosimetric procedures to be followed for the radiation-induced reproductive sterilization of live insects for use in pest management programs. The primary use of such insects is in the Sterile Insect Technique, where large numbers of reproductively sterile insects are released into the field to mate with and thus control pest populations of the same species. A secondary use of sterile insects is as benign hosts for rearing insect parasitoids. A third use is for testing detection traps for fruit flies and moths, and testing mating disruption products for moths. The procedures outlined in this document will help ensure that insects processed with ionizing radiation from gamma, electron, or X-ray sources receive absorbed doses within a predetermined range. Information on effective dose ranges for specific applications of insect sterilization, or on methodology for determining effective dose ranges, is not within the scope of this document. NOTE 1—Dosimetry is only one component of a total quality assurance program to ensure that irradiated insects are adequately sterilized and fully competitive or otherwise suitable for their intended purpose. 1.2 This document provides information on dosimetry for the irradiation of insects for these types of irradiators: selfcontained dry-storage 137Cs or 60Co irradiators, self-contained low-energy X-ray irradiators (maximum processing energies from 150 keV to 300 keV), large-scale gamma irradiators, and electron accelerators (electron and X-ray modes). NOTE 2—Additional, detailed information on dosimetric procedures to be followed in installation qualification, operational qualification, performance qualification, and routine product processing can be found in ISO/ASTM Practices 51608 (X-ray [bremsstrahlung] facilities processing at energies over 300 keV), 51649 (electron beam facilities), 51702 (large-scale gamma facilities), and 52116 (self-contained dry-storage gamma facilities), and in Ref (1)2 (self-contained X-ray facilities). 1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard except for the non-SI units of minute (min) hour (h) and day (d). These non-SI units are accepted for use within the SI system. 1.4 This document is one of a set of standards that provides recommendations for properly implementing and utilizing radiation processing. It is intended to be read in conjunction with ISO/ASTM Practice 52628. 1.5 The absorbed dose for insect sterilization is typically within the range of 20 Gy to 600 Gy. 1.6 This document refers, throughout the text, specifically to reproductive sterilization of insects. It is equally applicable to radiation sterilization of invertebrates from other taxa (for example, Acarina, Gastropoda) and to irradiation of live insects or other invertebrates for other purposes (for example, inducing mutations), provided the absorbed dose is within the range specified in 1.5. 1.7 This document also covers the use of radiation-sensitive indicators for the visual and qualitative indication that the insects have been irradiated (see ISO/ASTM Guide 51539). 1.8 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.9 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.
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归口单位: ISO/TC 85
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