MX可能是迄今为止在含氯消毒水中发现的最重要的单一诱变剂。这些研究的目的是通过反复给B6C3F1小鼠服用不同剂量的MX，并以Fischer速率测定MX对哺乳动物的毒性。大鼠的毒性表现为进食量和饮水量减少，以及高剂量MX时体重增加减少。在MX剂量为8、16和64 mg/kg体重的雄性小鼠中观察到类似的体重减轻。基于体重增加减少、胃损伤和其他变化，8 mg/kg被认为是小鼠和大鼠口服MX 14天的最低不良反应水平。 还需要进一步的研究来阐明饮用水中MX对人类健康的影响。包括13个参考文献和表格。

MX may be the most important single mutagen so far identified in chlorine-disinfected waters. The objective of these studies was to determine the toxicity of MX to mammals by repeatedly administering varying dosages of the compound to B6C3F1 mice and Fischer rates. Toxicity was evidenced in rats by decreased food and water consumption--and decreased body weight gain at a high MX dosage. Similar weight loss was observed in male mice at MX dosages of 8, 16, and 64 mg/kg body weight. Based on these decreased body weight gains, the presence of stomach lesions, and other changes, 8 mg/kg was considered to be the lowest adverse effect level for oral exposure to MX for 14 days in mice and rats. Additional research is required to elucidate the effect of MX in drinking water on human health. Includes 13 references, tables.