Various membrane technologies can help water purveyors meet tougher regulations and requirements. This paper presents a case study at the Salt Rock Water Treatment Plant to demonstrate that a combination of microfiltration (a membrane process) and conventional treatment helps save energy costs and membrane replacement costs, and offers a multi-barrier approach to treatment. Results of a pilot study, including Giardia and Coliform challenge tests, show that the microfiltration system capabilities meet and exceed current and pending regulatory requirements, despite a highly variable water supply source. A detailed capital and operational cost comparison shows microfiltration to be cost effective. Additionally, microfiltration offers various other advantages, such as improved water quality and a barrier against microbial contaminants. Generally, membrane filtration systems, such as microfiltration, have slightly higher capital and operational costs than conventional treatment plants. However, in certain situations, such as the one highlighted in this paper, microfiltration in combination with conventional treatment is cost effective and improves overall water quality.