ISO指南33:2015描述了在测量过程中使用标准物质（RMs），尤其是认证标准物质（CRM）的良好实践。这些用途包括评估测量方法的精度和真实性、质量控制、为材料赋值、校准和建立常规量表。本指南还将各种RMs的关键特性与不同的应用相关联。 对于标准物质管理系统，已经建立了属性值到国际尺度或其他测量标准的计量溯源性。对于不是CRM的RMs，通常没有建立这种属性值的可追溯性。 然而，这些RMs仍然可以用于评估部分测量程序，包括评估各种精度水平 RM的主流应用包括精度控制、偏差评估、校准、校准RMs的制备和维护常规量表。 注:并非所有类型的RMs都可用于所有指定用途。 校准RMs的准备也是ISO指南34和35范围的一部分。本指南中的处理仅限于实验室用于校准其设备的RMs小规模制备的基础知识和赋值。此类RMs的大规模生产以及可能的分销目的超出了本指南的范围。 ISO指南34和35涵盖了此类活动。 本指南不包括天然气分析、临床化学和制药行业中使用的工作标准的制定。ISO指南34和35涵盖了此类活动。

ISO Guide 33:2015 describes good practice in using reference materials (RMs), and certified reference materials (CRMs) in particular, in measurement processes. These uses include the assessment of precision and trueness of measurement methods, quality control, assigning values to materials, calibration, and the establishment of conventional scales. This Guide also relates key characteristics of various types of RMs to the different applications. For CRMs, the metrological traceability of the property values to international scales or other measurement standards has been established. For RMs not being CRMs, this kind of traceability of property values has often not been established. Nevertheless, these RMs can still be used for assessing parts of measurement procedures, including evaluating various levels of precision Mainstream applications of RM include precision control, bias assessment, calibration, preparation of calibration RMs and maintaining conventional scales. NOTE Not all types of RMs can be used for all indicated purposes. The preparation of RMs for calibration is also part of the scope of ISO Guides 34 and 35. The treatment in this Guide is limited to the fundamentals of small-scale preparation of RMs and the value assignment, as used by laboratories to calibrate their equipment. Larger scale production of such RMs, with the possible aim of distribution is beyond the scope of this Guide. This type of activity is covered in ISO Guides 34 and 35. The development of working standards, as used in, e.g. natural gas analysis, clinical chemistry, and the pharmaceutical industry is not covered in this Guide. This type of activity is covered in ISO Guides 34 and 35.