Determination of organonitrogen compounds in air using liquid chromatography and mass spectrometry — Part 2: Amines and aminoisocyanates using dibutylamine and ethyl chloroformate derivatives
用液相色谱和质谱法测定空气中的有机氮化合物第2部分:用二丁胺和氯甲酸乙酯衍生物的胺和氨基异氰酸酯
发布日期:
2013-11-27
ISO 17734-2:20 13为工作场所空气中空气中的胺和氨基异氰酸酯的采样和分析提供了一般指南。强烈建议胺和氨基异氰酸酯的测定与空气中异氰酸酯的测定一起进行,使用DBA作为试剂(参见ISO 17734-1)。
该方法可用于同时测定胺,如4,4'-亚甲基二苯基二胺(4,4'-MDA)、2,4-和2,6-甲苯二胺(2,4-和2,6-TDA)和1,6-六亚甲基二胺(1,6-HDA),以及同时含有异氰酸酯和胺基团的化合物,如4,4'-亚甲基二苯基氨基异氰酸酯(4,4'-MAI)、2,4-、4,2-和2,6-甲苯氨基异氰酸酯(2,4-、4,2-和2,6-TAI)和1,6-六亚甲基氨基异氰酸酯(1,6-HAI)。该方法适用于收集气相和颗粒相中的胺和氨基异氰酸酯。胺的仪器检测限为约5nmol/样品,氨基异氰酸酯的仪器检测限为约0.3 nmol/样品。对于15升空气样本,这相当于0.4纳克?m?TDA为3,0.03 ng?m?泰3。
ISO 17734-2:2013 gives general guidance for the sampling and analysis of airborne amines and aminoisocyanates in workplace air. It is strongly recommended that the determination of amines and aminoisocyanates is made together with the determination of isocyanates in air, using DBA as a reagent (see ISO 17734-1).
The method can be used for simultaneous determinations of amines, such as 4,4'-methylenediphenyldiamine (4,4'-MDA), 2,4- and 2,6-toluenediamine (2,4- and 2,6-TDA), and 1,6-hexamethylenediamine (1,6-HDA), and compounds containing both isocyanate and amine groups, such as 4,4'-methylenediphenyl aminoisocyanate (4,4'-MAI), 2,4-, 4,2-, and 2,6-toluene aminoisocyanate (2,4-, 4,2-, and 2,6-TAI), and 1,6-hexamethylene aminoisocyanate (1,6-HAI). The method is suitable for collecting amines and aminoisocyanates in both the gas and particle phases. The instrumental detection limit for the amines is about 5 nmol/sample and for the aminoisocyanate, it is about 0,3 nmol/sample. For a 15 l air sample, this corresponds to 0,4 ng?m?3 for TDA and 0,03 ng?m?3 for TAI.