在线固相萃取（SPE）与液相色谱联用 质谱（LC/MS/MS）用于检测来自不同组分的19种化合物 药物、杀虫剂、个人护理产品和类固醇的浓度低至 研究了饮用水和地表水中的NGL^-1。所有结果均显示出良好的一致性 再现性，所有样品的相对标准偏差（RSD）均小于12% 化合物。观察到一些化合物的基质效应，但不超过 超过25%。方法除雌三醇外，检测限在2-25ng L^-1范围内 其值为50纳克升^-1。在地表水中，回收率从87%到110%不等。这个 对各种水样进行分析，并检测和量化一些 还报告了选定的化合物。这种方法比传统的离线方法更受欢迎 程序，因为它可以最大限度地减少繁琐的样品制备和增加 生产率包括12个参考文献、表格和图表。

On-line solid phase extraction (SPE) was coupled to liquid chromatography with tandem mass spectrometry (LC/MS/MS) to detect 19 compounds from a diverse group of pharmaceuticals, pesticides, personal care products and steroids at a concentration as low as ng L^-1 in drinking and surface waters was studied. All results displayed a good degree of reproducibility, with relative standard deviations (RSD) of less than 12 % for all compounds. Matrix effects were observed for some compounds without exceeding more than 25%. Method detection limits were in the range of 2 to 25 ng L^-1 except for estriol with a value of 50 ng L^-1. The recoveries varied from 87 to 110 % in surface waters. The analysis of various water samples with the detection and quantification of some of the selected compounds were also reported. This method was preferred over traditional offline procedures since it can minimize tedious sample preparation and increases productivity. Includes 12 references, tables, figures.