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现行 ISO/TR 14735:2013
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Cosmetics — Analytical methods — Nitrosamines: Technical guidance document for minimizing and determining N-nitrosamines in cosmetics 化妆品和化妆品;分析方法——亚硝胺:化妆品中最小化和测定N-亚硝胺的技术指导文件
发布日期: 2013-04-10
ISO/TR 14735:2013旨在为减少化妆品中N-亚硝胺形成的可能性而采取的策略提供一般性建议,并描述可靠测定化妆品中N-亚硝胺的分析方法。它还试图对所述每种方法的相关性和局限性提供一些见解,并最终为化妆品和原材料中N-亚硝胺的分析提供一种分析方法。 ISO/TR 14735:2013涵盖了减少或消除不定亚硝酸盐源、减少或消除次级氨基源、加入抑制剂以形成N-亚硝胺、总N-亚硝基化合物的分析方法以及N-亚硝二乙醇胺(NDELA)的具体方法。
ISO/TR 14735:2013 aims to contribute to providing general advice on strategies that can be adopted to minimize the likelihood of N-nitrosamine formation in cosmetic products and provide a description of the analytical methodologies available for the reliable determination of N-nitrosamines in cosmetic products. It also seeks to provide some insight into the relevance and limitations of each of the methods described and finally provide an analytical approach for the analysis of N-nitrosamines in cosmetic products and raw materials. ISO/TR 14735:2013 covers the reduction or elimination of adventitious nitrite sources, reduction or elimination of secondary amino sources, incorporation of inhibitors to N-nitrosamine formation and analytical methodologies for total N-nitroso compounds and specific methods for N-nitrosodiethanolamine (NDELA).
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归口单位: ISO/TC 217
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