ISO 29701:2010描述了使用鲎变形细胞裂解物(LAL)试剂的测试在评估用于基于细胞的体外生物测试系统的纳米材料中的应用。该测试适用于分散在水性介质(例如水、血清或反应介质)中的纳米材料样品，以及在37℃下与纳米材料温育适当持续时间的此类介质。 ISO 29701:2010仅限于体外系统的测试样品，但该方法也可适用于通过肠胃外途径施用于动物的纳米材料。

ISO 29701:2010 describes the application of a test using Limulus amebocyte lysate (LAL) reagent for the evaluation of nanomaterials intended for cell-based in vitro biological test systems. The test is suitable for use with nanomaterial samples dispersed in aqueous media, e.g. water, serum or reaction medium, and to such media incubated with nanomaterials for an appropriate duration at 37 °C. ISO 29701:2010 is restricted to test samples for in vitro systems, but the methods can also be adapted to nanomaterials to be administered to animals by parenteral routes.