Different types of mathematical models have been developed for usein drinking water distribution. Generale des Eaux of Paris la Defense, France, utilizes two models: SANCHO and SWS. SANCHO is a microbiological model, which allows for the simulation of the degradation of microbiological quality in a distribution network. In its initial form, the SANCHO model calculates the evolution of chlorine concentration, biodegradable dissolved organic matter (BDOC) concentration and biomass of fixed and free bacteria in pipes in which the diameter is decreasing as a function of residence time. SWS is a hydraulic model that performs quasidynamic hydraulic calculations. This paper explains how these models have been joined to create a new model that allows the prediction of the evolution of bacterial regrowth in the network, the location of high microbiological risk zones depending on treated water qualityand the geometry of the distribution system. The paper summarizes tests and analyses conducted with the new model on a full-scale distribution network. Includes 41 references, tables, figures.