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A New Breakthrough Process Using DNA Chip Technology for Controlling the Microbiological Quality of Water 利用DNA芯片技术控制水质微生物的新突破
发布日期: 2003-11-02
苏伊士环境公司和BIOMERIEUX之间的工业伙伴关系 SA的成立是为了联合开发世界上第一个使用 DNA芯片技术,由Affymetrix,Inc.技术支持,该技术允许 在不到一天的时间内对水样中的细菌、寄生虫和病毒进行多重检测。这个 由Affymetrix(加利福尼亚州)提供的GeneChip®品牌技术是一项成熟、成熟的技术 这项技术是该应用的重大突破,因为它允许快速 在一次分析中对病原体进行多重检测,而不是多次单一检测试验。 该研究项目开发了一个原型,代表了一个完整的分析过程 从30L水样制备到13种微生物的多重检测。研究 为样本制备和基因组选择提供了产品和试剂 序列,以及用于多重检测的生物信息学算法的开发。 这一新过程的速度(不到一天,而病毒只需数周)以及对活的水传播病原体的特殊多重检测将使其成为可能 以更好的方式评估和防范潜在风险。这也将改善决策- 制作 关于使用的最佳治疗方法,并允许更快地恢复正常操作 在市政、三级(公共建筑、医院等)或工业部门(食品和药品) 饮料、化妆品、药品等)。 这一新工艺将通过以下方式提高消费者的安全性: 允许更快更好地评估潜在风险。它还将带来新的知识 研究微生物在水循环中的发生情况,以便更好地决策,确保水的可持续性。包括30个参考文献、表格、图表。
An industrial partnership between SUEZ ENVIRONNEMENT and BIOMERIEUX SA was established in order to jointly develop the first analytical process in the world using DNA chip technology, powered by Affymetrix, Inc. technology, which allows the multidetection of bacteria, parasites, and viruses in water samples in less than a day. The GeneChip® brand technology supplied by Affymetrix (California) is an established, proven technology that constitutes a major breakthrough for this application since it allows rapid multidetection of pathogens in one single analysis instead of several monodetection tests. This research program developed a prototype, which represents a complete analytical process from a 30L water sample preparation to the multidetection of 13 microorganisms. Research has come up with the product and reagents for sample preparation, choice of the genomic sequences, and development of the bio-informatics algorithm for multidetection. The speed of this new process (less than a day as opposed to weeks for viruses) and the specific multidetection of viable waterborne pathogens will make it possible to assess and protect against potential risks in a better way. It will also improve decision-making about the best treatments to use and allow faster return to normal operations whether in the municipal, tertiary (public buildings, hospitals, etc.) or industrial sectors (Food and Beverage, Cosmetics, Pharmaceuticals, etc.). This new process will enhance the consumer's safety by allowing much faster and better evaluation of potential risks. It will also bring new knowledge on the occurrence of microorganisms along the water cycle, allowing better decision-making to ensure water sustainability. Includes 30 references, table, figures.
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发布单位或类别: 美国-美国给水工程协会
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