本文基于ASHRAE研究项目RP-1472的研究结果。冷冻手术是一种通过冷冻过程来破坏癌症等不良组织的技术。为用于冷冻手术的两级混合气体焦耳-汤姆逊（MGJT）冷冻探针开发了热力学建模工具。使用纯制冷剂的常规蒸汽压缩（VC）循环预冷却MGJT循环，该循环在低温探针尖端提供制冷。该模型与优化程序一起用于研究不同低温探针尖端温度以及最佳预冷温度下的最佳混合物组成。 cryoprobe系统的性能根据cryoprobe尺寸、压缩机尺寸和功耗进行报告。将两级系统的结果与单级MGJT循环的性能进行比较，以证明添加预冷循环的好处和局限性。单位:双引文:ASHRAE交易，第115卷，第。2、路易斯维尔2009

This paper is based on findings resulting from ASHRAE Research Project RP-1472.Cryosurgery is a technique for destroying undesirable tissue such as cancers using a freezing process. A thermodynamic modeling tool was developed for a two stage, mixed gas Joule-Thomson (MGJT) cryoprobe used for cryosurgery. A conventional Vapor Compression (VC) cycle using a pure refrigerant pre-cools the MGJT cycle that provides refrigeration at the cryoprobe tip. The model is used with an optimization routine to investigate the optimal mixture composition for different cryoprobe tip temperatures as well as optimal precooling temperatures. The cryoprobe system performance is reported in terms of cryoprobe size, and compressor size and power consumption. The results for the two stage system are compared with the performance of a single stage MGJT cycle to demonstrate the benefits and limitations associated with the addition of the precooling cycle.Units: Dual