本powerpoint演示文稿首先简要概述铀，包括放射性、毒性、健康影响和美国环境保护局（USEPA）放射性核素规则。以弗吉尼亚州丁威迪县为例，从1980年到2004年，该县的铀（U）水平得到了监测 范围为80-101微克/升，平均比标准高3倍 美国环保局MCL。弗吉尼亚州卫生部（VDH）决定，必须对有问题的油井进行处理 监控以实现对新MCL的遵守。进行了一项流行病学研究，以确定当前的尿液浓度 受影响居民中的铀（U治疗前），并评估其潜在危险 对参与者的肾脏造成损害，并重复生物监测1年。 稍后（之后） U治疗）（怀亚特等人，2008年）。该研究包括pH值、铀、视黄醇结合蛋白的测量 （RBP）和参与者尿液样本中的肌酐水平。选择离子交换技术作为实验方法，研究结论表明:居民饮用水中的U水平与U水平直接相关 在居民家庭中发现的一个社区供水系统可以制作；饮用水中铀含量超过美国环保局30微克/升的MCL是一个令人担忧的问题 水因为已知的铀毒性而影响肾功能；在丁威迪县的一个小社区，U水平是正常水平的3倍 美国环保局（USEPA）对饮用水的MCL，这导致尿液中的铀浓度高 来自参与流行病学研究的居民的样本；而且，在WRT的U治疗系统之前，3名参与者的血液中RBP浓度较高 尿液显示肾脏损伤的初始阶段，但已降至正常 WRT U治疗系统投入使用6个月后RBP水平。包括表格、数字。

This powerpoint presentation begins by providing a brief overview of uranium, including radioactivity, toxicity, health effects, and the U.S. Environmental Protection Agency (USEPA) Radionuclide Rule. The case of Dinwiddie County, Virginia is presented where uranium (U) levels monitored from 1980-2004 ranged from 80-101 µg/L, which is on average 3 times above the USEPA MCL. The Virginia Department of Health (VDH) determined that the wells in question had to be monitored to achieve compliance with the new MCL. An epidemiology study was conducted to determine current concentrations of urine uranium (before U treatment) in affected residents and evaluate potential damage to the participant's kidneys and repeat biomonitoring 1 yr. later (after U treatment) (Wyatt et al. 2008). The study included measurements of pH, uranium, retinol-binding protein (RBP), and creatinine levels from participants' urine samples. Ion exchange technology was selected for experimental approach, and study conclusions indicate that: a direct correlation of U levels in residential drinking water with U levels found in residents of households of a Community Water System can be made; levels of uranium above the USEPA MCL of 30 µg/L are a concern in drinking water because of the known uranium toxicity affecting kidney function; in a small community in Dinwiddie County, U levels measured 3 times the USEPA MCL for drinking water, which resulted in high U concentrations in urine samples from residents that participated in an epidemiological study; and, before WRT's U treatment system, high RBP concentrations in 3 participants' urine indicated initial stages of damage to kidneys but decreased to normal RBP levels 6 months after WRT's U treatment system became operational. Includes tables, figures.