ISO 11641:2012规定了在所有加工阶段测定各种皮革耐汗渍色牢度的方法。它特别适用于手套、服装和衬里皮革，以及无衬里鞋的鞋面皮革。 该方法使用人工排汗溶液来模拟人类排汗的行为。由于每个人的排汗差异很大，因此不可能设计出具有普遍有效性的方法，而是ISO 11641中规定的碱性人工排汗溶液: 2012年的结果将与大多数情况下自然出汗的结果一致。

ISO 11641:2012 specifies a method for determining the colour fastness to perspiration of leather of all kinds at all stages of processing. It applies particularly to gloving, clothing and lining leathers, as well as leather for the uppers of unlined shoes. The method uses an artificial perspiration solution to simulate the action of human perspiration. Since perspiration varies widely from one individual to the next, it is not possible to design a method with universal validity, but the alkaline artificial perspiration solution specified in ISO 11641:2012 will give results corresponding to those with natural perspiration in most cases.