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Low Dose Risks from Bromate: The Relationship between Drinking Water Concentrations and the Actual Dose to Susceptible Organs in Rats and Humans, Pre-systemic Decomposition 溴酸盐的低剂量风险:饮用水浓度与大鼠和人类易感器官的实际剂量之间的关系 系统前分解
发布日期: 2007-06-01
本powerpoint演示文稿的研究策略是:发展基于生理学的 量化器官剂量的药代动力学模型 低剂量摄入和毒性反应;和 低剂量的毒性反应机制。 这导致: 重新审查MCLG的依据;和 修订低剂量的风险评估。涵盖的主题包括:系统前分解;溴酸盐在饮用水中的重要性 水供应商;溴酸盐健康风险总结;关键风险评估问题;关键风险评估问题;为什么风险评估很重要;以前的研究;溴酸盐化学和动力学;溴酸盐研究项目概述;溴酸盐模型 毒代动力学;体内运输和分解;我们现在在哪里;目前的研究从2007年4月到2009年1月。
This powerpoint presentation's research strategy was: to develop Physiologically Based Pharmacokinetic Model to quantify organ dose from ingestion and toxic responses at low dose; and, a mechanism of toxic response at low doses. This leads to: re-examination of basis for MCLG; and, revision of risk assessment at low doses. Topics covered include: Pre-systemic Decomposition; the importance of Bromate in Drinking Water to Water Suppliers; Bromate Health Risk Summary; Critical Risk Assessment Issues; Critical Risk Assessment Issues; Why Risk Assessment Matters; Previous Research; Bromate Chemistry and Kinetics; Bromate Research Program Overview; Model of Bromate Toxicokinetics; Transport and Decomposition in vivo; Where are we now-summary; and, Current Study-April 2007 to January 2009.
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发布单位或类别: 美国-美国给水工程协会
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