溴酸盐通常由饮用水中的溴化物臭氧氧化生成 被确定为人类致癌物。目前，溴酸盐受到监管 在10 ug/L的饮用水中，美国环境保护局（USEPA）采用了300.1 B、317.0和326.0方法 经美国环保局批准用于合规性监测。高浓度 常见的阴离子，如氯化物、硫酸盐和碳酸盐，可能会产生不良反应 溴酸盐的峰形状和回收率较低。这通常需要分析师 稀释提高最低报告限（MRL）的样品或进行预处理 样品在分析前离线。 样品的预处理需要 增加了每次分析的时间和成本。因此，本项目的目标 消除高浓度基体离子的方法 尽量减少干扰。本文介绍了两种新的美国环保局待定方法 使用二维（2D）离子色谱（IC）。在第一维度中，一个 将大回路注入4 mm高容量离子交换柱上，以分离 溴酸盐来自基质阴离子。溴酸盐可通过自动过滤系统选择性去除 阀门切换到浓缩器柱上。在第二维度，溴酸盐 使用2mm阴离子交换柱进行第二次分离，然后 抑制电导检测后的定量。这种策略允许 能够注入大量样本，在第一时间部分分解溴酸盐 将尺寸标注到浓缩器柱上，并在第二个更高的位置将其分离 解析栏。它还结合了两种不同的色谱柱化学成分，以增强 选择性和减少误报的可能性，并消除 第二栏确认。这种方法也改进了美国环保局的方法 314.0和314.1用于测定饮用水中的高氯酸盐，即使在 高盐基质的存在（>1000 mg/L的Cl^-，因此₄和NO₃）。新的 该方法可使信号增强4倍，从而降低检测率 限值（0.016微克/升）。仅包含摘要。

Bromate is commonly formed from the ozonation of bromide in drinking water and is determined to be a human carcinogen. Currently, bromate is regulated in drinking water at 10 ug/L. U.S. Environmental Protection Agency (USEPA) Methods 300.1 B, 317.0, and 326.0 are approved by the USEPA for compliance monitoring. High concentrations of common anions, such as chloride, sulfate, and carbonate, can produce poor bromate peak shapes and lower recoveries. This often requires the analyst to either dilute the sample which raises the minimum reporting limit (MRL) or pretreat the sample offline prior to analysis. Pretreatment of samples requires increased time and cost for each analysis. Therefore, the objective of this project was to develop a method that eliminates high concentrations of matrix ions and minimizes interferences. This paper describes two new USEPA pending methods using two-dimensional (2D) ion chromatographic (IC). In the first dimension, a large loop is injected on a 4-mm high capacity ion exchange column to separate bromate from matrix anions. Bromate is selectively removed using automated valve switching onto a concentrator column. In the second dimension, Bromate is separated a second time using a 2-mm anion exchange column followed by quantitation after suppressed conductivity detection. This strategy allows the ability to inject large sample volumes, focus bromate partially resolved in the first dimension onto a concentrator column and separate it on a second, higher resolution column. It also combines two different column chemistries to enhance selectivity and reduce the possibility of false positives and eliminates the need for second column confirmation. This method also improves upon USEPA Method 314.0 and 314.1 for the determination of perchlorate in drinking water, even in the presence of high salt matrices (>1,000 mg/L for Cl^-, SO₄ and NO₃). The new method results in a 4-fold signal enhancement, which yields a lower detection limit (0.016 µg/L). Includes abstract only.