Inactivation of Cryptosporidium by Chlorine Dioxide at 1 Degree C
1℃二氧化氯灭活隐孢子虫
发布日期:
1998-01-01
在1℃下使用二氧化氯在实验室规模上研究了氯化铯纯化的牛源微小隐孢子虫卵囊的失活。在pH值为6的200 mL 0.05 M磷酸盐缓冲液中使用温度控制水浴进行实验。新生CD-1小鼠的感染性用于评估治疗后的卵囊活力。据观察,一个简单的CT(应用剂量x接触时间)产品约为150毫克。在1摄氏度时,最小/升导致约0.5对数单位的失活。对于相似的CT值,约2对数单位的失活-
在22摄氏度时观察到失活单位。
Inactivation of cesium chloride purified, bovine-derived Cryptosporidium parvum oocysts was studied at bench-scale using chlorine dioxide at 1 degree C. Experiments were conducted in 200 mL of 0.05 M phosphate buffer at pH 6 using a temperature controlled water bath. Infectivity of neonatal CD-1 mice was used for evaluation of oocyst viability following treatment. It was observed that a simple CT (applied dose x contact time) product of about 150 mg.min./L resulted in about 0.5 log-units of inactivation at 1 degree C. For a similar CT value, about two log-units of inactivation was observed at 22 degrees C.