ISO 13344:2015提供了一种估算材料在物理火灾模型的特定燃烧条件下产生的火灾流出物致命毒性的方法。致死毒性效力值与选择的火灾模型、暴露场景和评估的材料具体相关。 使用燃烧空气分析数据预测与大鼠30分钟暴露相关的致死毒性效力值，这些数据包括一氧化碳（CO）、二氧化碳（CO2）、氧气（O2）（滴定）和氰化氢（HCN）、氯化氢（HCl）、溴化氢（HBr）、氟化氢（HF）、二氧化硫（SO2）、二氧化氮（NO2），丙烯醛和甲醛。 试样的化学成分可能会建议量化并包括其他燃烧产物。如果火灾排放物的毒性不能归因于所分析的毒物，则表明必须考虑其他毒物或因素。 ISO 13344:2015适用于评估受控实验室条件下材料、产品或组件产生的火灾流出物大气的致命毒性，不应单独用于描述或评估实际火灾条件下材料、产品或组件的毒性危险或风险。 然而，该试验的结果可作为火灾危险评估的要素，该评估考虑了与特定最终用途火灾危险评估相关的所有因素；参见ISO 19706。 消防安全工程计算的预期用途是预测人的生命安全，最常见的是时间间隔略短于30分钟。这种跨物种和暴露间隔的推断不在ISO 13344:2015的范围内。 ISO 13344:2015并非旨在解决与其使用相关的所有安全问题。 ISO 13344:2015的用户有责任建立适当的安全和健康实践。

ISO 13344:2015 provides a means for estimating the lethal toxic potency of the fire effluent produced from a material while exposed to the specific combustion conditions of a physical fire model. The lethal toxic potency values are specifically related to the fire model selected, the exposure scenario and the material evaluated. Lethal toxic potency values associated with 30-min exposures of rats are predicted using calculations which employ combustion atmosphere analytical data for carbon monoxide (CO), carbon dioxide (CO2), oxygen (O2) (vitiation) and, if present, hydrogen cyanide (HCN), hydrogen chloride (HCl), hydrogen bromide (HBr), hydrogen fluoride (HF), sulfur dioxide (SO2), nitrogen dioxide (NO2), acrolein and formaldehyde. The chemical composition of the test specimen may suggest additional combustion products to be quantified and included. If the fire effluent toxic potency cannot be attributed to the toxicants analysed, this is an indication that other toxicants or factors must be considered. ISO 13344:2015 is applicable to the estimation of the lethal toxic potency of fire effluent atmospheres produced from materials, products or assemblies under controlled laboratory conditions and should not be used in isolation to describe or appraise the toxic hazard or risk of materials, products or assemblies under actual fire conditions. However, results of this test may be used as elements of a fire hazard assessment that takes into account all of the factors which are pertinent to an assessment of the fire hazard of a particular end use; see ISO 19706. The intended use of fire safety-engineering calculations is for life-safety prediction for people and is most frequently for time intervals somewhat shorter than 30 min. This extrapolation across species and exposure intervals is outside the scope of ISO 13344:2015. ISO 13344:2015 does not purport to address all of the safety problems associated with its use. It is the responsibility of the user of ISO 13344:2015 to establish appropriate safety and health practices.