MSS SP-146-2019 covers the construction requirements for high pressure, lug-, wafer-, and flange-type iron and ductile iron knife gate valves.This Standard Practice covers flanged body designs compatible with the following ASME standardized flanges:(a) B16.1, Class 125 flanges for sizes NPS 2 (DN 50) through NPS 60 (DN 1500);(b) B16.1 Class 250 flanges for sizes NPS 2 (DN 50) through NPS 48 (DN 1200);(c) B16.42 Class 150 and 300 flanges for sizes NPS 2 (DN 50) through NPS 24 (DN 600).