The design and operation of a small full-scale ion exchange system used to remove uranium from well water in the foothills west of Denver, Colorado, are described. Consistent removal of uranium was accomplished by anion exchange treatment at a reasonable cost. Because of a lack of clear regulatory guidelines, disposal of the uranium-laden regenerant wastewater was the most complicated task associated with this treatment system. Gamma radiation buildup did not appear to be a health concern. Includes 9 references, tables, figures.