1.1 本试验方法包括测定从工作场所和环境空气中采集的空气样品中的气态六亚甲基二异氰酸酯（HDI）。本试验方法中描述的方法收集单独的部分。一部分将由蒸汽控制，另一部分将由气溶胶控制。从单独部分的分析中获得的结果不一定代表测量的HDI物理相的真实分配，而应仅被视为代表样本内物理相分配的一般趋势。这两个分数的分析是不同的，以单独、链接的标准提供，以避免混淆。本试验方法主要用于确定在工作场所环境中进行个人监测或在环境空气中的短期HDI暴露（15分钟）。按照试验方法中的描述，单独进行气溶胶成分的分析 D6561 . 1.2 差分空气采样使用分离装置进行。蒸汽部分收集在浸渍有9-（N-甲胺甲基）蒽（MAMA）的玻璃纤维过滤器（GFF）上。 1.3 本试验方法的应用范围已在0.006至1.12μg单体HDI/2.0 mL解吸溶液之间进行了验证，其对应的浓度相当于0.0004至0.075 mg/m 3. 基于15升空气样本的HDI。这些浓度对应于0.06 ppb（V）至11 ppb（V）的汽相浓度范围，并涵盖5 ppb（V）的既定阈值限制值（TLV）。 1.4 使用紫外检测法确定单体HDI的定量限为0.012μg/2 mL解吸溶液，使用荧光检测器确定为0.008μg/2 mL。这些限值对应于0.0008 mg/m 3. 和0.0005 mg/m 3. 分别适用于15 L的空气采样体积。 这些值等于在与GFF接触的标准溶液上进行的十次测量得到的标准偏差（SD）的十倍，GFF的浓度为0.02μg/2 mL，接近预期检测限。 1.5 以国际单位制表示的数值应视为标准值。本标准不包括其他计量单位。 1.6 本标准并非旨在解决与其使用相关的所有安全问题（如有）。本标准的用户有责任在使用前制定适当的安全、健康和环境实践，并确定监管限制的适用性。 参见第节 9 其他危险。 1.7 本国际标准是根据世界贸易组织技术性贸易壁垒（TBT）委员会发布的《关于制定国际标准、指南和建议的原则的决定》中确立的国际公认标准化原则制定的。 ====意义和用途====== 5.1 HDI主要用于涂料的制备。异氰酸酯的使用及其工业需求一直在不断增长。 5.2 二异氰酸酯和多异氰酸酯对皮肤、眼睛和粘膜有刺激性。它们被认为会引起呼吸道过敏性致敏、哮喘性支气管炎和急性呼吸道中毒 ( 4- 7. ) . 5.3 美国政府工业卫生学家会议（ACGIH）采用了0.005 ppm（V）或0.034 mg/m的阈值-时间加权平均值（TLV-TWA） 3. ( 8. ) . 美国劳工部职业安全与健康管理局（OSHA）尚未列出人类发展指数的允许接触限值（PEL） ( 9 ) . 5.4 无论如何，对于蒸汽和气溶胶没有单独的暴露标准。因此，在将异氰酸酯的结果与标准品进行比较时，应将两种馏分的结果结合起来，得出一个总值。 5.5 由于其低LOD和低所需体积（15 L），该试验方法非常适合监测与二异氰酸酯和多异氰酸酯相关的呼吸和其他问题。其采样时间短，与许多工业过程的持续时间相适应，其低检测限与工作区域中经常发现的浓度相适应。

1.1 This test method covers the determination of gaseous hexamethylene diisocyanate (HDI) in air samples collected from workplace and ambient atmospheres. The method described in this test method collects separate fractions. One fraction will be dominated by vapor, and the other fraction will be dominated by aerosol. The results obtained from the analysis of the separate fractions do not necessarily represent the true partition of the measured HDI physical phases, and should only be considered a representation of the general trend in the physical phase partition within samples. The analyses of the two fractions are different, and are provided in separate, linked, standards to avoid confusion. This test method is principally used to determine short term exposure (15 min) of HDI in workplace environments for personal monitoring or in ambient air. The analysis of the aerosol fraction is performed separately, as described in Test Method D6561 . 1.2 Differential air sampling is performed with a segregating device. The vapor fraction is collected on a glass fiber filter (GFF) impregnated with 9-(N-methylaminomethyl) anthracene (MAMA). 1.3 The range of application of this test method has been validated from 0.006 to 1.12 μg of monomeric HDI/2.0 mL of desorption solution, which corresponds to concentrations equivalent to 0.0004 to 0.075 mg/m 3 of HDI based on a 15 L air sample. Those concentrations correspond to a range of vapor phase concentrations from 0.06 ppb(V) to 11 ppb(V) and cover the established threshold limit value (TLV) value of 5 ppb(V). 1.4 The quantification limit for the monomeric HDI, using the UV detection, has been established as 0.012 μg/2 mL of desorption solution and as 0.008 μg/2 mL, using the fluorescence detector. These limits correspond to 0.0008 mg/m 3 and 0.0005 mg/m 3 respectively for an air sampled volume of 15 L. These values are equal to ten times the standard deviation (SD) obtained from ten measurements carried out on a standard solution in contact with the GFF, whose concentration of 0.02 μg/2 mL is close to the expected detection limit. 1.5 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard. 1.6 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. See Section 9 for additional hazards. 1.7 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee. ====== Significance And Use ====== 5.1 HDI is mostly used in the preparation of paints. The use of isocyanates and their industrial needs have been in constant growth. 5.2 Diisocyanates and polyisocyanates are irritants to skin, eyes, and mucous membranes. They are recognized to cause respiratory allergic sensitization, asthmatic bronchitis, and acute respiratory intoxication ( 4- 7 ) . 5.3 The American Conference of Governmental Industrial Hygienists (ACGIH) has adopted a threshold limit value – time weighted average (TLV – TWA) of 0.005 ppm (V) or 0.034 mg/m 3 ( 8 ) . The Occupational Safety and Health Administration of the U.S. Department of Labor (OSHA) has not listed a permissible exposure limit (PEL) for HDI ( 9 ) . 5.4 In any case, there are not separate exposure standards for vapor and aerosol. Therefore, in comparing the results for isocyanate against a standard, results from the two fractions should be combined to give a single total value. 5.5 Due to its low LOD and low required volume (15 L), this test method is well suited for monitoring of respiratory and other problems related to diisocyanates and polyisocyanates. Its short sampling times are compatible with the duration of many industrial processes, and its low detection limit with the concentrations often found in the working area.