使用基于分离的高氯酸盐处理技术（如离子交换或膜）的一个缺点是，它们产生的高氯酸盐浓度必须进行处理或去除 进一步治疗。“常规”生物工艺可用于处理高氯酸盐残留物 但通常需要一个专门的除氧步骤，即接种外源耐盐菌 由于溶液的高盐度，以及添加昂贵的外源性底物（如乙醇），细菌的停留时间较长。一种处理高氯酸盐残留物的新方法是 将其与去皮的城市污水混合，然后在固定床（FXB）中处理 生物反应器。城市污水降低了溶解氧浓度 （DO抑制高氯酸盐降解），降低溶液盐度（盐度降低 生物降解动力学），并提供必要的基质和细菌。本文讨论了一个为期六个月的试点项目 这项研究调查了这种治疗概念在富含高氯酸盐的电渗析中的应用 反转（EDR）浓缩。该研究表明:在FXB生物反应器中，使用约0.5的混合比，可以实现并维持高氯酸盐去除至检测以下（~4 g/L） （废水:EDR浓缩液）和空床接触时间（EBCT）低至10分钟；该过程对系统故障具有鲁棒性；颗粒活性炭（GAC） 作为生物生长支持培养基，有效尺寸约为2 mm是最佳选择。

A disadvantage of using separation-based perchlorate treatment technologies (e.g. ion exchange or membranes) is that they produce a perchlorate-laden concentrate that must be disposed or further treated. "Conventional" biological processes can be used to treat perchlorate residuals but typically require a dedicated deoxygenation step, inoculation with exogenous salt-tolerant bacteria, long residence times due to high solution salinities, and the addition of a costly exogenous substrate such as ethanol. A novel approach for treating perchlorate residuals is to blend them with scalped municipal wastewater followed by treatment in a fixed-bed (FXB) bioreactor. The municipal wastewater decreases the bulk dissolved oxygen (DO) concentration (DO inhibits perchlorate degradation), decreases solution salinity (salinity decreases biodegradation kinetics), and provides the requisite substrate and bacteria. This paper discusses a six-month pilot study investigating the application of this treatment concept to perchlorate-laden electrodialysis reversal (EDR ) concentrate. The study demonstrated that: perchlorate removal to below detection (~4 g/L) can be achieved and sustained in a FXB bioreactor using blend ratios around 0.5 (wastewater:EDR concentrate) and empty-bed contact times (EBCTs) as low as 10 minutes; the process is robust with respect to system upsets; and, that granular activated carbon (GAC) with an effective size of approximately 2 mm was optimal as a biogrowth support medium.