本文件描述了通过测量在规定的气溶胶化程序后释放的气溶胶，对从处理到高能分散的粉末中释放的纳米物体进行量化的方法。测量了气溶胶的粒子数浓度和粒径分布，导出了质量浓度。本文件提供了在选择粉末取样和处理程序的可用方法时应考虑的因素的信息，并规定了试验样品制备、试验方案制定、测量颗粒释放和报告数据的最低要求。 为了表征生成的颗粒的全尺寸范围，本文件中讨论了纳米物体以及团聚体和聚集体的测量。本文件不包括粉末中颗粒尺寸的表征。如果直接机械摩擦用于研磨或研磨材料，则不包括摩擦学方法。购买本文件时可获得的所有当前修订均包含在购买本文件中。

This document describes methods for the quantification of nano-object release from powders as a result of treatment, ranging from handling to high energy dispersion, by measuring aerosols liberated after a defined aerosolization procedure. Particle number concentration and size distribution of the aerosol are measured and the mass concentration is derived. This document provides information on factors to be considered when selecting among the available methods for powder sampling and treatment procedures and specifies minimum requirements for test sample preparation, test protocol development, measuring particle release and reporting data. In order to characterize the full size range of particles generated, the measurement of nano-objects as well as agglomerates and aggregates is addressed in this document.This document does not include the characterization of particle sizes within the powder. Tribological methods are excluded where direct mechanical friction is applied to grind or abrade the material.All current amendments available at time of purchase are included with the purchase of this document.