The 1986 amendments to the Safe Drinking Water Act mandate the establishment of new drinking water quality and treatment regulations. In fulfilling this mandate, the US Environmental Protection Agency is in the process of developing, proposing, and promulgating drinking water quality regulations that will significantly change water treatment practice and water utility operations. New regulations for volatile organic chemicals, fluoride, surface water treatment, and total coliform bacteria have been promulgated. Regulations for synthetic organic and inorganic chemicals and lead and copper have been proposed. Regulations for radionuclides, additional synthetic organic and inorganic chemicals, and disinfectants and disinfection byproducts are under development. The history, content, current status, and schedule of new or anticipated regulatory actions are reviewed. Includes 45 references, tables, figure.