ISO 16638-1:2015规定了监测接触铀化合物工人的专业计划设计的最低要求。它确立了为职业性暴露于内部污染的工人制定监测计划和剂量评估兼容目标和要求的原则。它为风险分析、监测计划和监测数据的标准化解释建立了程序和假设，以实现铀及其化合物的可接受可靠性水平。它针对剂量水平对程序的适用性设定了限制，超过该水平时，必须采用更复杂的方法。 铀在放射和化学上都有毒。因此，除了辐射暴露限值外，还审查了现行职业暴露标准的科学依据。本国际标准针对辐射或化学毒性问题可能限制接触的情况。 ISO 16638-1:2015规定了铀及其化合物的以下项目: a） 监测和监测方案的目的； b） 说明不同类别的监测方案； c） 实施监测方案的量化标准； d） 适当的监测方法及其选择标准； e） 为设计监测方案而必须收集的信息； f） 监测计划的一般要求（例如检测限、容许不确定性）； g） 测量频率； h） 基于常规和特殊监测计划参考水平的剂量评估程序； i） 选择剂量临界参数值的假设； j） 确定监测结果重要性的标准； k） 解释工作场所监测结果； l） 剂量评估和生物测定数据解释产生的不确定性； m） 报告/文件； n） 质量保证； o） 记录保存要求。 不适用于以下项目: a） 监测铀子体（包括氡）的暴露； b） 铀测量方法和技术的详细说明； c） 诉讼案件的剂量测定； d） 改进内部剂量学的建模； e） 应对措施的潜在影响（例如使用螯合剂）； f） 调查接触的原因或影响； g） 摄入暴露和污染伤口的剂量测定。

ISO 16638-1:2015 specifies the minimum requirements for the design of professional programmes to monitor workers exposed to uranium compounds. It establishes principles for the development of compatible goals and requirements for monitoring programmes and dose assessment for workers occupationally exposed to internal contamination. It establishes procedures and assumptions for risk analysis, monitoring programmes and the standardised interpretation of monitoring data in order to achieve acceptable levels of reliability for uranium and its compounds. It sets limits for the applicability of the procedures in respect to dose levels above which more sophisticated methods have to be applied. Uranium is both radiologically and chemically toxic. Hence, the scientific bases of current occupational exposure standards are reviewed in addition to radiation exposure limits. This International Standard addresses those circumstances when exposure could be constrained by either radiological or chemical toxicity concerns. ISO 16638-1:2015 addresses, for uranium and its compounds, the following items: a) purposes of monitoring and monitoring programmes; b) description of the different categories of monitoring programmes; c) quantitative criteria for conducting monitoring programmes; d) suitable methods for monitoring and criteria for their selection; e) information that has to be collected for the design of a monitoring programme; f) general requirements for monitoring programmes (e.g. detection limits, tolerated uncertainties); g) frequencies of measurements; h) procedures for dose assessment based on reference levels for routine and special monitoring programmes; i) assumptions for the selection of dose-critical parameter values; j) criteria for determining the significance of monitoring results; k) interpretation of workplace monitoring results; l) uncertainties arising from dose assessment and interpretation of bioassays data; m) reporting/documentation; n) quality assurance; o) record keeping requirements. It is not applicable to the following items: a) monitoring of exposure due to uranium progeny, including radon; b) detailed descriptions of measuring methods and techniques for uranium; c) dosimetry for litigation cases; d) modelling for the improvement of internal dosimetry; e) potential influence of counter-measures (e.g. administration of chelating agents); f) investigation of the causes or implications of an exposure; g) dosimetry for ingestion exposures and for contaminated wounds.