ISO 11641:2012规定了在各种加工阶段确定各种皮革出汗色牢度的方法。它特别适用于手套，服装和衬里皮革，以及无衬里鞋面上的皮革。 该方法使用人造汗水解决方案来模拟人体出汗的作用。由于汗水从一个人到另一个个体差异很大，所以不可能设计出具有普遍有效性的方法，但是ISO 11641:2012中规定的碱性人造汗水解决方案在大多数情况下会给出与自然汗水相符的结果

ISO 11641:2012 specifies a method for determining the colour fastness to perspiration of leather of all kinds at all stages of processing. It applies particularly to gloving, clothing and lining leathers, as well as leather for the uppers of unlined shoes. The method uses an artificial perspiration solution to simulate the action of human perspiration. Since perspiration varies widely from one individual to the next, it is not possible to design a method with universal validity, but the alkaline artificial perspiration solution specified in ISO 11641:2012 will give results corresponding to those with natural perspiration in most cases.