This standard specifies the minimum operational and performance requirements of active interrogation systems for use in homeland security applications. These systems employ penetrating ionizing radiation (e.g., neutrons, high-energy x-rays, gamma-rays) to detect and identify hidden special nuclear material, explosives, and chemical warfare agents by the detection of stimulated secondary radiations or by nuclear resonance contrast, giving elemental and/or isotopic identification of the composition of the substances-of-interest. These inspection systems may be designed for open inspection zones of various sizes or for various sizes of containers such as small packages, briefcases, suitcases, air cargo containers, passenger vehicles, two-axle trucks, intermodal cargo containers, semi-trailers/tractor rigs, or rail cars. The systems may be designed for operation in indoor, outdoor, or mobile facilities. This standard does not apply to small portable systems.