Distribution system water quality is affected by a great many factors. Biofilms are often the result of interactions between exisitng piping systems which have some deposits or growth, and which experience some form of contamination through disinfection breakdown, or through the entrance of pathogens into the system. It is not always necessary for the pipe to have been in use for a period of time, however. Installation and maintenance practices can also impact water quality, even in new pipe. This paper will explore some of the common influences which are not always considered, and provide some insight into practical solutions that have been demonstrated to be effective. Case studies are given.