隐孢子虫卵囊对传统的氯基消毒剂具有高度抗性。在全尺寸（400 gpm）条件下测试了一种利用紫外线照射的创新方法对隐孢子虫卵囊的灭活能力。基于这些分析的局限性，体外替代物（脱囊、DAPI/PI和SYTO染料）显示至少2-log失活。使用新生小鼠模型进行的动物感染性研究显示，在三个单独的试验中，隐孢子虫失活>4对数。 这项技术似乎是一种处理饮用水的新方法，为保护公众健康提供了额外的重要障碍。

Cryptosporidium oocysts are highly resistant to conventional chlorine-based disinfectants. An innovative method using ultraviolet irradiation was tested at full-scale (400 gpm) for its ability to inactivate Cryptosporidium oocysts. In vitro surrogates (excystation, DAPI/PI and the SYTO dyes) indicated at least 2-log inactivation based on the limitations of those assays. Animal infectivity studies using the neonatal mouse model showed a >4-log inactivation of Cryptosporidium in three separate trials. The technology appears to be a novel way to treat drinking water and provide an additional significant barrier in protecting public health.